YBX1 and acute myeloid leukemia: Overexpressed in AML, IGF2BPs are crucial in the maintenance of the disease state.YBX1, a protein that is integral to AML, interacts with IGF2BPs, thereby stabilizing tumor-related genes that contain m6A mRNAs, such as V-Myc Avian Myelocytomatosis Viral Oncogene Homolog (MYC) and BCL2 Apoptosis Regulator (BCL2) [111].