Given the association of stress granules with chemotherapy resistance, targeting their assembly could offer a promising therapeutic strategy to overcome both primary and acquired resistance, thereby enhancing treatment efficacy.27,28,32,33 However, the precise mechanisms underlying stress granule formation are not fully understood, and the role of HNRNPA1 in driving oncogenic processes in cancer requires further elucidation. This evidence concerns the gene HNRNPA1 and cancer.