ANXA5 and neoplasm: However, stress granules can also suppress the apoptosis of cancer cells.33,53 To investigate whether the tumor suppressive roles of ZMYND11 are due to stress granules-induced apoptosis, we analyzed the apoptosis rate of control and ZMYND11 knockdown groups after 1 h of treatment with SA, using Annexin V-488 and PI double-stained flow cytometry.