More specifically, CD8+ cytotoxic T-cell responses have been found to be an essential contributor to the protection against severe coronavirus disease–COVID-19—by clearing infected cells, especially in the setting of minimal antibody responses [6], while CD4+ helper T-cells are important for protective antibody responses holding an assistive role for CD8+ T-cells’ maturation and proliferation [7]. The gene discussed is CD8A; the disease is COVID-19.