INS and hydrops fetalis: In female mice, HF mice had significantly higher glucose tolerance (two-way ANOVA diet × RS status, p < 0.0001; Tukey’s HSD: p = 0.0006 (Figure 6A)) but similar insulin levels during an OGTT (two-way ANOVA diet × RS status, p = 0.004; Tukey’s HSD: p = 0.1906 (Figure 6B)) and glucose levels during an ITT (two-way ANOVA diet × RS status, p = 0.0234; Tukey’s HSD: p = 0.0502 (Figure 6C)) compared to control mice.