FGF23 and chronic kidney disease: Goto et al. [74] disclosed that an LPD (0.60–0.80 g of protein/kg of body weight/day, 10–15 mg of phosphorus/kg of body weight/day, and 30–35 Kcal/kg of body weight/day) for 4 to 6 days reduced circulating FGF23 both in early (n = 15; mean age of 45 y; 13% men) and advanced (n = 20; mean age of 66 y; 65% men) CKD.