ALB and Enlarged kidney: Thus, in the present study, all the recoveries in histological changes could be related to the improvement in hyperglycaemia and could be associated with the attenuation of weight loss, reduced hepato- and nephromegaly, as well as with the alleviation of renal hyperfiltration, which in turn is connected with reduced levels of serum creatinine and urinary glucose and albumin [26,27].