It is worth mentioning that in HaCaT cells treated with Doxorubicin (10 μM) for 48 h, β-actin protein was not detected since Doxorubicin is a powerful cell death agent that causes the degradation of cytoskeleton components; this does not compromise the Western Blot results since it demonstrates the effect of different stimuli on the tumor cell phenotypes of greatest interest [33]. Here, ACTB is linked to neoplasm.