In view of this, anti-inflammatory agents (non-steroidal anti-inflammatory drugs, peroxisome proliferator-activated receptor-γ activators, minocycline, and anti-TNFα drugs: thalidomide, etanercept) were evaluated for their potential utility as DMTs in AD, but the results obtained were discouraging [5,6,7,116,117,118]. Here, TNF is linked to Alzheimer disease.