GRPR and neoplasm: Notably, during NEP inhibition, the specificity of tumor uptake could be clearly illustrated in the significant reduction in the animals treated with single NT (for NTS1R-blockade), [Tyr4]BBN (for GRPR-blockade) or double-receptor ligand (s) (NT+[Tyr4]BBN for NTS1R/GRPR-blockade).