NR4A1 and triple-negative breast carcinoma: To elucidate if the effects of the combined treatments of auraptene with tamoxifen-derived metabolites are specific to BC cells that overexpress ER+, the triple-negative breast cancer cell model lacking expression of hormone receptors, MDA-MB-231 (MDA) cell line, which shows the main phenotypic properties of TNBC cancer, was evaluated.