Additionally, LCH facilitates autophagy and apoptosis in hepatocellular carcinoma cells through the inactivation of the tongue cancer resistance-associated protein (TCRP1)/Protein kinase B (Akt)/mammalian target of rapamycin (mTOR) (TCRP1/Akt/mTOR) signaling pathway. The gene discussed is AKT1; the disease is hepatocellular carcinoma.