A significant difference in lung Csf3 and Cxcl1 protein levels between MHV68-infected wild-type and tumor-bearing mice was observed and appears to correlate with the differential lung recruitment of MDSCs as assessed by mRNA levels of Cd84, Jaml, and Trem2 expression in the lung and detection of CD45+CD11b+Ly6G+ and CD45+CD11b+Ly6GDimLy6C+ cells by flow cytometry. The gene discussed is CSF3; the disease is neoplasm.