Despite the minimal higher level of MAVS-Fis1 colocalization in Mdivi-1-treated cells and insignificant changes in CCCP-treated cells during ECTV infection, mitochondrial network modifications increase the opportunity for MAVS and Fis1 colocalization in both ECTV-infected and noninfected-control murine fibroblasts. This evidence concerns the gene MAVS and infection.