After identifying these potential mechanisms of action, the following search queries were included: (2) (small intestine bacterial overgrowth) AND (chronic pancreatitis); (3) (small intestine bacterial overgrowth) AND (probiotics OR prebiotics OR synbiotics); (4) (short-chain fatty acid) AND (pancreas*); (5) (short-chain fatty acid) AND (probiotics OR prebiotics OR synbiotics); (6) (GLP-1) AND (pancreas*); and (7) (GLP-1) AND (probiotics OR prebiotics OR synbiotics). This evidence concerns the gene GCG and chronic pancreatitis.