SLC2A4 and Insulin resistance: Excess free fatty acids in the cytoplasm serve as a source of precursors for the synthesis of molecules such as diacylglycerol and ceramides, which participate in the development of insulin resistance, culminating in the inhibition of the translocation of vesicles containing the glucose transporter type 4 (GLUT 4) to the plasma membrane of myocytes and adipocytes, thus reducing glucose uptake and contributing to an increase in blood glucose levels [19].