GPT and central core myopathy: When evaluating the liver and kidney nontoxicity of CCO at the dose used, no significant difference in alanine aminotransferase (ALT), aspartate aminotransferase (AST), blood urea nitrogen (BUN), and creatinine (CREA) was observed between the sham (SH) and CCO in rats treated with 300 mg/kg of CCO for 5 days (Figure 1).