Lung cancer induction significantly depleted the concentration of glutathione (GSH) and significantly inhibited the activities of its related enzymes, glutathione reductase (GR), glutathione S transferase (GST), and glutathione peroxidase (GPx), in lung cancer, compared to the negative control group (p ≤ 0.05) (Table 1). The gene discussed is HPGDS; the disease is lung carcinoma.