The typical lipid abnormalities associated with obesity include elevated levels of TGs, very low-density lipoprotein (VLDL), and apolipoprotein B (Apo B), while HDL and apolipoprotein A-I (Apo A-I) levels are generally low, and LDL levels are usually normal or slightly elevated [22,23,24]. This evidence concerns the gene APOB and obesity due to melanocortin 4 receptor deficiency.