In a study conducted by Liu et al., it was noted that in various bacterial and parasite infections, M2 macrophages protect the body from excessive tissue damage by clearing apoptotic cells and inducing regeneration [81]; hence, connecting the functions of these two factors, it can be suggested that this positive correlation between them indicates mutual synergy, where Gal-10 creates tissue inflammation to protect it from invaders but M2 macrophages work alongside it to clear the created debris and to preserve the tissue from extreme inflammatory damage;. This evidence concerns the gene CLC and infection.