KMT2C and cancer: The CGI results revealed 14 cancer driver mutations in 12 genes: EPHA2, NSD1, BUB1B, CTNND1, KAT6A, MUTYH, MAP3K13, MUC4, KMT2C, VAV1, BIRC6, NF1, and MUC4 (Supplementary Table S4).