When analyzing the original breast cancer, the median value of estrogen receptor expression was 90% (95% CI 87.4–90.0, ranging from 8 to 100), progesterone receptor 37.5% (95% CI 22.0–55.0, ranging from 0 to 100), and Ki67 23.0% (95% CI 21.4–25.0, ranging from 1 to 85). This evidence concerns the gene ESR1 and breast carcinoma.