TGFB1 and chronic rhinosinusitis with nasal polyps: In our study, we observed elevated levels of eosinophiles in the blood of CRSwNP patients compared to NC patients, as well as a positive correlation between blood eosinophile counts and tissue CNPase levels in both CRSwNP and CRSsNP patients, and with TGFβ1 in CRSwNP patients.