CD40 and Crohn disease: Marzano et al. reported supporting evidence of common genetic and cytokine profiles with Crohn’s disease, including Fas ligand, cluster of differentiation 40 (CD40+) ligand, interleukin-8 (IL-8), chemokine (C-X-C Motif) ligands 1, 2, 3 (CXCL 1/2/3), CXCL 16, and CCL5, also known as regulated on activation, normal T-cell expressed and secreted (RANTES) [28].