STAT4 rs10181656 CG + GG genotypes were found to increase the odds of a T2 size carcinoma by 4.1-fold under the dominant model (OR = 4.126, 95% CI: 2.326–7.320, p < 0.001), and each G allele of the rs10181656 is associated with 3-times increased odds of developing LSCC with a T2 tumor size (OR = 3.035, 95% CI: 2.003–4.599, p < 0.001) (Table 10). Here, STAT4 is linked to neoplasm.