This work investigated the link between the exposure to some environmental pollutants, from persistent organic pollutants to some non-persistent plasticizers and antimicrobials, and thyroid disorders in type 1 diabetes children. Associations between the levels (in serum or urine) of some PFASs, PCBs, phthalates and bisphenols and thyroid hormone were highlighted, suggesting an impact of these pollutants on the thyroid function in this population suspected to be particularly vulnerable toward endocrine disruption. This evidence concerns the gene TG and type 1 diabetes mellitus.