Furthermore, the KEGG pathway analysis results revealed that 17 TRDEGs showed significant enrichment in various pathways, including the interaction between cytokines and their receptors, viral protein interactions with cytokines and receptors, the JAK-STAT signaling pathway, and the chemokine signaling pathway, as well as in diseases such as pertussis, leishmaniasis, and rheumatoid arthritis. This evidence concerns the gene SOAT1 and rheumatoid arthritis.