CD68 is not thought to be involved in bacterial/viral pathogen binding, innate, inflammatory or humoral immune responses, although it could potentially be involved in antigen processing/presentation, while macrophages devoid of CD68 show normal phagocytic activity and do not exhibit a defective innate response to infection; they have a normal ability to present antigens and induce a humoral immune response [25]. Here, CD68 is linked to infection.