Considering the above-mentioned premises, the aim of the present study is to find innovative antitumor molecules, possibly developable as new topical treatments for counteracting CMM; the anticancer effects of a BTPP-BA molecule have been investigated for the first time on two BRAF mutant’s melanoma cell lines, which commonly exhibit pigmentation on skin of the head, under the armpits, of the abdomen, and of the legs [60]. The gene discussed is BRAF; the disease is melanoma.