Neither gene has biological function that is obviously related to viral pathogenesis, but, again, related paralogues encode proteins which have previously been associated with influenza virus: AKAP10 binds to polymerase PA-PB1 [34], while AKAP13 is involved in early steps of viral replication [17], and SLC25A25 facilitates host–cell resistance to lethal influenza challenge [35]. This evidence concerns the gene AKAP13 and influenza.