PLPP3 and glaucoma: In this regard, terms referring to subcellular compartments involved in cell adhesiveness and lipid metabolism, with phospholipid phosphatase 3 emerging as the protein with the highest log2FC, motility and secretion polarity support a conceptual correlation with the dysregulation of the TM typical of glaucoma pathogenesis and, in particular, the stiffness of the TM, which impairs the AH drainage.