The patterns of seven cytokines (CXCL10, MCP-1, IL-6, IL-10, CXCL8, GCSF, and CCL3) were more complex and difficult to interpret in TTP, which may be due to a variety of reasons, such as the genetic characteristics of the patients or the effect of immunosuppressive therapy. This evidence concerns the gene IL6 and thrombotic thrombocytopenic purpura.