Figure 6 depicts a Venn diagram of the overlap of DAGs between the different comparisons, illustrating an overlap of 8 human genes between all comparisons, which represents tumor-specific signals, irrespective of humanization: PHF14, PELP1, RPL7L1, HPRT1, RELN, RNU1-75P, RNU5A-8P, and RNVU1-19. The gene discussed is RNU5A-1; the disease is neoplasm.