The most abundant up-regulated proteins in the wild stage were chitinase, mucin 19 proteins, histone H1, deleted in malignant brain tumors 1 protein-like, adhesion G-protein coupled receptor, cytochrome c oxidase copper chaperone, neutral and basic amino acid transport protein rBAT, protocadherin Fat 4, barrier-to-autointegration factor B, SCO-spondin protein, caspase 7, 60S ribosomal protein L13 and L7, protocadherin Fat 4, ras-related protein Rab-3, and MAM-LDL-receptor class A domain-containing protein. The gene discussed is SLC3A1; the disease is brain cancer.