PIK3CA and glaucoma: Zhao et al. [37] reported that baicalin could inhibit N-methyl-D-aspartate (NMDA)-induced apoptosis, autophagy, and oxidative stress in retinal ganglion cells (RGCs) by activating the PI3K-AKT signaling pathway in vitro and in vivo, thereby slowing pathological changes in the retinal tissues of glaucoma mice.