MPO and antiphospholipid syndrome: Notably, evidence has demonstrated that antiphospholipid antibodies (aPLs) and anti-β2GPI antibodies isolated from patients with antiphospholipid syndrome (APS) can induce human neutrophils to release NETs as well as massive expressions of ROS, Cit-H3, and myeloperoxidase (MPO) [10,13,14,15].