In addition, it interacts with immune evasion mechanisms and signaling pathways involved in thromboregulation and thrombosis in cancer-associated [100], e.g., some studies indicate that clotting protease thrombin, FVIIa, and FXa contribute to cancer immune evasion via unique mechanisms such as TF/FVIIa/PAR2 signaling [101]. This evidence concerns the gene TF and cancer.