Nevertheless, among patients with localised disease at cancer diagnosis and treated with AbA for mCRPC management, significant associations were found concerning hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 1 (HSD3B1) rs1047303 (CC/CA vs. AA; log-rank test, p = 0.014; Figure 2a), YBX1 rs12030724 (AT vs. AA; log-rank test, p = 0.027; Figure 2b) and YBX1 rs10493112 (CC vs. AA/AC; log-rank test, p = 0.041; Figure 2c). This evidence concerns the gene HSD3B1 and cancer.