TNF and Alzheimer disease: Despite having a similar visceral fat mass, the serum concentrations of TNF-α were much higher in the AD-CON group compared to the Normal-CON group and lower in the AD-RVT, AD-ZXT, and AD-LTN groups (p < 0.05), indicating that resveratrol, zeaxanthin, and lutein supplementation suppressed its increment (Table 2).