As mentioned, MEN1, with an autosomal dominant predisposition to tumors of the parathyroid glands, anterior pituitary, and pancreatic islet cells, associates with multiple cutaneous lesions such as angiofibromas, lipomas, and collagenomas, and, potentially, an increased risk of other non-endocrine malignancies [177,178]. This evidence concerns the gene MEN1 and tumor of parathyroid gland.