Regarding the mediating pathways between WC and pneumonia, CRP, IL-6, and FEV1 mediated 26.90% (95% CI: 13.98%, 39.83%), 10.23% (95% CI: 2.72%, 17.73%), and 4.67% (95% CI: 0.25%, 9.09%) of the effect of WC on pneumonia, respectively (Figure 2 and Supplementary Table S10). The gene discussed is CRP; the disease is susceptibility to pneumonia measurement.