Raised AST levels signify liver dysfunction, which in turn contributes to bleeding tendency through several mechanisms [26] such as impaired synthesis of clotting factors including prothrombin and fibrinogen, vitamin K deficiency, a possibility of impending disseminated intravascular coagulation (DIC), thrombocytopenia, and endothelial dysfunction leading to impaired blood vessel integrity. This evidence concerns the gene F2 and endothelial dysfunction.