ALB and Cirrhosis: The activation of the cytokine cascade and the production of NO in cirrhosis and SBP negatively impacts kidney function; therefore, the use of intravenous albumin (1.5 g/kg within 6 h of SBP followed by 1 g/kg on day 3) in conjunction with cefotaxime reduces the incidence of kidney failure from 33% to 10% and the incidence of mortality from 29% to 10%.