Furthermore, analyzing the group of treated women (n.32, 11%) in which myoinositol failed to prevent GDM, it is noteworthy that this group of women with GDM had, in the first trimester, a statistically (p = 0.01) significant higher insulin resistance (HOMA = 2.97 ± 1.7) compared to the placebo GDM group (HOMA = 2.30 ± 2.2). Here, INS is linked to gestational diabetes.