The post-operatory biomarker thyroglobulin represents a routinely performed analysis for differentiated thyroid cancer in cases with persistence or recurrence; however, after lobectomy/near-total/hemi-thyroidectomy, this marker has a limited use because it can be secreted either by the remaining cancerous cells or by the normal residual thyroid tissue [88,89,90]. This evidence concerns the gene TG and thyroid gland carcinoma.