Genotype information is also useful to select for certain genotypes that are responsible for particular traits or inherited conditions, e.g., Fading Calf Syndrome, Chediak Higashi Syndrome, Claudin 16 Deficiency, Band 3 Spherocytosis, and Factor XI deficiency. This evidence concerns the gene CLDN16 and hyperinsulinemic hypoglycemia, familial, 4.