Good examples of the 37 significantly immune-imbalanced genes we found already in use as drug targets for both lupus and lymphoma which could be targeted using gene therapy are CD3g Molecule (CD3G; C+A− quadrant), Janus Kinase 1 (JAK1; C−A+ quadrant), and Prostaglandin-Endoperoxide Synthase 1 (PTGS1; C−A− quadrant). Here, CD3G is linked to systemic lupus erythematosus.