Figure 6 illustrates the 15 main pathways with the highest degree of enrichment, which included cellular phenomena linked to metabolism, biosynthesis, and protein manipulation. This finding underscores the pivotal position of EGFR in orchestrating varied cellular functions across numerous molecular channels. Notably, ‘pathway in cancer’ included 21 associated proteins, representing a compelling argument for the regulatory control exerted by EGFR during MDCK cell tumor initiation. Table 3 provides comprehensive details regarding these 21 interacting proteins. This evidence concerns the gene EGFR and neoplasm.