One explanation of our result regarding the nonsignificant difference between adiponectin values at 24–28 weeks of pregnancy in OW/OB pregnant women with and without GDM is that we included in the study pregnant women with pre-pregnancy BMI ≥ 25 Kg/m2, while Ramirez et al. [51] included only obese pregnant women with a BMI ≥ 30 Kg/m2, and it is known that adiponectin maternal levels are inversely correlated with maternal BMI [52]. This evidence concerns the gene ADIPOQ and gestational diabetes.