The clinicopathological characteristics of both tumors revealed the diagnosis of poorly differentiated, metaplastic/matrix-producing carcinoma (G3), with ER-0%, PR-0%, HER-2-0, and Ki-67-90% from the first tumor and poorly differentiated invasive ductal carcinoma (G3), with ER-0%, PR-0%, HER-2-0, and Ki-67-75% from the second tumor. The gene discussed is ERBB2; the disease is invasive ductal breast carcinoma.