ICAM1 and endothelial dysfunction: Resistin promotes endothelial dysfunction by increasing the expression of adhesive molecules (intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1))), facilitates the adhesion of monocytes to the endothelium and increases the permeability of endothelial cells, which means that more lipoproteins penetrate the vessel wall and contribute to plaque formation [38,39].